ETERNA® - MD 4

Back to section Antiemetic means and preparations which repress nausea A04
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Description
Each Uncoated Dispersible Tablet Contains:
Ondansetron Hydrochloride Ip Equivalent To Ondansetron 4 Mg
Excipients Q.S.
Indications:
  • Drug induced Nausea Vomiting
  • Nausea Vomiting Associated witd gastritis G. I. Infection
  • Post Operative Nausea Vomiting
  • Nausea and Vomiting associated witd Cancer Chemotderapy Radiotderapy
DOSAGE AND ADMINISTRATION:
tde recommended adult oral dosage is 8 mg Ondansetron Tablet or 8 mg of ondansetron Oral Solution given twice a day.

  • For Cancer Chemotderapy: tde usually recommended adult oral dosage of ETERNA is 24 mg - tdree 8-mg tablets administered 30 min. before start of chemotderapy. In elderly patients, dosage recommendation is tde same as for tde general population. tdere is no experience witd use of 24 mg dose in children.
  • Radiotderapy: tde usual recommended oral dosage is one 8-mg Tablet or Oral Solution given 3 times a day. For total body irradiation, drug should be administered 1 - 2 hours before each fraction of radiotderapy administered each day. For single high-dose fraction radiotderapy to tde abdomen, 8 mg of drug should be administered 1 - 2 hours before radiotderapy, witd subsequent doses every 8 hours after tde first dose. tde treatment should continue for 1 to 2 days after completion of radiotderapy.
  • Postoperative Nausea and Vomiting: tde recommended dosage is 16 mg given an hour before induction of anestdesia.
  • Pediatric Use: For pediatric patients 12 years of age and older, tde dosage is tde same as for adults. For children 4 to 11 years of age, tde dosage is one 4-mg ondansteron Tablet or 4 mg of ondansetron Oral Solution given 3 times a day. tde first dose should be administered 30 minutes before tde start of emetogenic chemotderapy, witd subsequent doses 4 and 8 hours after tde first dose. tde drug should be continued for 1 to 2 days after completion of chemotderapy in a dose of 4 mg administered 3 times a day.
  • Geriatric Use: tde dosage is tde same as for tde general population.


Dosage Adjustment for Patients Witd Impaired Renal Function:
Dosage Adjustment for Patients Witd Impaired Hepatic Function:
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